Clinical Research Details

Splenic Size and Platelet Levels After Embolization for Traumatic Injury

Study Description

The purpose of this study will be to investigate the relationship between splenic artery embolization and platelet levels and splenic volume for patients in the trauma setting.

We will obtain this information via a retrospective chart review from September 1, 2009 to September 1, 2019. We will first identify potential patients on the UF trauma registry. Our inclusion criteria includes any report of splenic artery embolization or CPT code “37244” within the impression or findings of the radiology report for any trauma patient within the allotted time range. The exclusion criteria includes not receiving splenic artery embolization for trauma. For each patient, we will then access their data on EPIC and Visage PACS to record their platelet levels from their complete blood count at initial intake and at least three months after intervention and record organ volume measurements on CT at initial intake and at least three months after intervention. We will also measure the distance of embolization on follow up imaging from the splenic hilum on follow up CT. This data will be statistically analyzed using SAS statistical software.

Our study population will be identified within the UF trauma registry and will be listed on a password encrypted Excel spreadsheet. Data will be stored in an Office of Research Affairs “phile drive”, which is only accessible on an UF IT approved server that is password protected and encrypted. The excel sheet will also be password protected, and the unique code will only be distributed to the study staff on this IRB. When we go through the registry list and search through their medical records on EPIC and Visage PACS, the data we need to collect and patient information will de identified with a unique numeric code. The de-identified information gathered from EPIC will be placed in a separate Excel spreadsheet and coded with the recordings of platelet levels and spleen volume at intake and after three months. We will obtain spleen volume by measuring the spleen on each patient's scan. This database that we create from that information will henceforth be used for the statistical analysis and manuscript. The code will be destroyed at the end of the chart review.


Principal Investigator
Daniel A. Siragusa, M.D.